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Wilforlide A
CAS No. 84104-71-2
Wilforlide A( Wilforlide A | Regelide | Abruslactone A )
Catalog No. M19164 CAS No. 84104-71-2
Wilforlide A is a natural product separated from the ethanolic extract of tripterygium wilfordii.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 54 | In Stock |
|
| 5MG | 96 | In Stock |
|
| 10MG | 134 | In Stock |
|
| 25MG | 242 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameWilforlide A
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NoteResearch use only, not for human use.
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Brief DescriptionWilforlide A is a natural product separated from the ethanolic extract of tripterygium wilfordii.
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DescriptionWilforlide A, also known as Regelide and Abruslactone A, is an active compound in Tripterygium wilfordii Hook F (TW) which is a traditional Chinese medicine for treatment of autoimmune diseases, is a quality control marker for TW product.
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In Vitro——
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In VivoWilforlide A (60-300 μg/kg) markedly inhibits mice auricular swelling induced by dimethylbenzene in ICR mice. Wilforlide A exhibits inhibition rates with 50.9% and 12.29% for high dose and low dose Wilforlide A, resepectively. Wilforlide A (30-150 μg/kg) markedly inhibits rat granulation induced by tampon.
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SynonymsWilforlide A | Regelide | Abruslactone A
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PathwayMetabolic Enzyme/Protease
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TargetLipase
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RecptorOthers
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number84104-71-2
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Formula Weight454.7
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Molecular FormulaC30H46O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 1 mg/mL (2.20 mM)
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SMILESO[C@@H]1C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C)[C@H]6OC(=O)[C@](C)(C6)C[C@H]5C4=CC[C@@H]3[C@]2(CC1)C
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Chemical Name(2S,5S,5aR,7aS,7bR,9aR,11S,13aR,13bR,15bS)-11-hydroxy-2,5a,7a,7b,10,10,13a-heptamethyl-1,5,5a,6,7,7a,7b,8,9,9a,10,11,12,13,13a,13b,14,15b-octadecahydro-2,5-methanochryseno[2,1-c]oxepin-3(2H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Xue M, et al. Fitoterapia. 2010 Dec;81(8):1109-12.
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